VARIJABILNOST KRVNOG PRITISKA I INDEKS LEVE KOMORE KOD DECE SA PRAVOM AMBULANTNOM HIPERTENZIJOM
DOI:
https://doi.org/10.46793/PP160829009BKljučne reči:
krvni pritisak, hipertenzija, varijabilnost, decaApstrakt
Ovom studijom se nastojalo da se proceni odnos između varijabilnosti krvnog pritiska i indeksa mase leve komore (LVMI) kod dece sa pravom ambulantnom hipertenzijom. Uradili smo studiju preseka kod 115 dece koja su bila upućena na Univerzitetsku dečiju klinuku za procenu hipertenzije. Varijabilnost krvnog pritiska (BPV) vrednosti su izračunate uz pomoć 24 časovne prosečne realne varijabilnosti (ARV) i 24 časovnog ponderisanog proseka srednjih vrednosti (wSD). LVMI je procenjena uz pomoć M-mod ehokardiografije upotrebom Devereux formule i indeksom visine. Ukupno 35 dece je imalo pravu ambulatornu hipertenziju. Nismo našli korelaciju između 24 časovne ARV i wSD sa LVMI. Sa druge strane, parcijalna korelacijona analiza pokazuje statističku signifikantnu i obrnutu korelaciju između 24 časovne ARV i LVMI, kontrolom indeksa telesne mase
(r = -0,516; P = 0.002). Za razliku od ranijih studija, naši rezultati pokazuju obrnutu povezanost LVMI i BPV, koja je iskazana preko ARV u populaciji dece sa pravom arterijskom hipertenzijom.
Reference
McNiece KL, Gupta-Malhotra M, Samuels J, Bell C, Garcia K, Poffenbarger T, et al. Left ventricular hypertrophy in hypertensive adolescents: analysis of risk by 2004 National High Blood Pressure Education Program Working Group staging criteria. Hypertension [Internet]. 2007 Aug [cited 2015 Jan 3];50(2):392–5. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3582191&tool=pmcentrez&rendertype=abstract
Sorof JM, Cardwell G, Franco K, Portman RJ. Ambulatory Blood Pressure and Left Ventricular Mass Index in Hypertensive Children. Hypertension [Internet]. 2002 Apr 1 [cited 2015 Jan 3];39(4):903–8. Available from: http://hyper.ahajournals.org/cgi/doi/10.1161/01.HYP.0000013266.40320.3B
Target H, Damage O. Large Blood Pressure Variability and Hypertensive Cardiac Remodeling. 2009;73(December):2198–203.
Shah R V, Abbasi S a, Neilan TG, Hulten E, Coelho-Filho O, Hoppin A, et al. Myocardial tissue remodeling in adolescent obesity. J Am Heart Assoc [Internet]. 2013 Aug [cited 2015 Jan 3];2(4):e000279. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3828806&tool=pmcentrez&rendertype=abstract
Nadruz W. Myocardial remodeling in hypertension. J Hum Hypertens [Internet]. 2015 Jan [cited 2015 Aug 30];29(1):1–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24804791
Mangner N, Scheuermann K, Winzer E, Wagner I, Hoellriegel R, Sandri M, et al. Childhood obesity: impact on cardiac geometry and function. JACC Cardiovasc Imaging [Internet]. 2014 Dec [cited 2015 Aug 30];7(12):1198–205. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25306542
de Simone G, Izzo R, De Luca N, Gerdts E. Left ventricular geometry in obesity: Is it what we expect? Nutr Metab Cardiovasc Dis [Internet]. 2013 Oct [cited 2015 Aug 28];23(10):905–12. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24095148
Chen W-K, Yeh Y-L, Lin Y-M, Lin J-Y, Tzang B-S, Lin JA, et al. Cardiac hypertrophy-related pathways in obesity. Chin J Physiol [Internet]. 2014 Jun 30 [cited 2015 Aug 30];57(3):111–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24826779
Murakami K, Shigematsu Y, Hamada M, Higaki J. Insulin Resistance in Patients With Hypertrophic Cardiomyopthy. 2004;68(July):650–5.
Martinka P, Fielitz J, Patzak A, Regitz-Zagrosek V, Persson PB, Stauss HM. Mechanisms of blood pressure variability-induced cardiac hypertrophy and dysfunction in mice with impaired baroreflex. Am J Physiol Regul Integr Comp Physiol [Internet]. 2005 Mar [cited 2015 Jan 3];288(3):R767–76. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15563577
Flynn JT, Daniels SR, Hayman LL, Maahs DM, McCrindle BW, Mitsnefes M, et al. Update: ambulatory blood pressure monitoring in children and adolescents: a scientific statement from the American Heart Association. [Internet]. Hypertension. 2014 [cited 2014 Dec 3]. 1116-35 p. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24591341
Soergel M, Kirschstein M, Busch C, Danne T, Gellermann J, Hall R, et al. Oscillometric twenty-four-hour ambulatory blood pressure values in healthy children and adolescents : A multicenter trial including 1141 subjects. 1997;
Pierdomenico SD, Di Nicola M, Esposito AL, Di Mascio R, Ballone E, Lapenna D, et al. Prognostic value of different indices of blood pressure variability in hypertensive patients. Am J Hypertens [Internet]. Nature Publishing Group; 2009 Aug [cited 2015 Jan 3];22(8):842–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19498342
Agabiti-Rosei E, Muiesan ML, Salvetti M. Evaluation of subclinical target organ damage for risk assessment and treatment in the hypertensive patients: left ventricular hypertrophy. J Am Soc Nephrol [Internet]. 2006 Apr [cited 2015 Jan 3];17(4 Suppl 2):S104–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16565230
Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, et al. CDC growth charts: United States. Adv Data. 2000;(314):1–27.
Stolarz-Skrzypek K, Thijs L, Richart T, Li Y, Hansen TW, Boggia J, et al. Blood pressure variability in relation to outcome in the International Database of Ambulatory blood pressure in relation to Cardiovascular Outcome. Hypertens Res [Internet]. 2010 Aug [cited 2015 Sep 16];33(8):757–66. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20613762
Calcaterra I, Costanzo M, Geraci G, Guarino L, Foraci AC. Relationship Between Short-Term Blood Pressure Variability and Subclinical Renal Damage in Essential Hypertensive Patients Relationship Between Short-Term Blood Pressure Variability and Subclinical Renal Damage in Essential Hypertensive Patients. 2015;(MARCH).
Stauss HM, Bjelakovic B. Re: Pediatric Hypertension and Cardiac Hypertrophy. Curr Hypertens Rep [Internet]. 2016 Jan [cited 2016 Jan 17];18(1):5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26739585
Vishram JKK, Dahlöf B, Devereux RB, Ibsen H, Kjeldsen SE, Lindholm LH, et al. Blood pressure variability predicts cardiovascular events independently of traditional cardiovascular risk factors and target organ damage: a LIFE substudy. J Hypertens [Internet]. 2015 Dec [cited 2016 Jan 17];33(12):2422–30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26378687
Mena L, Pintos S, Queipo N V, Aizpúrua JA, Maestre G, Sulbarán T. A reliable index for the prognostic significance of blood pressure variability. J Hypertens [Internet]. 2005 Mar [cited 2015 Sep 16];23(3):505–11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15716690
Li Z, Snieder H, Su S, Harshfield GA, Treiber FA, Wang X. A longitudinal study of blood pressure variability in African-American and European American youth. J Hypertens. 2010;28(4):715–22.
Höcht C, Bertera FM, Taira CA. Importance of blood pressure variability in the assessment of cardiovascular risk and benefits of antihypertensive therapy. Expert Rev Clin Pharmacol [Internet]. 2010 Sep [cited 2015 Sep 22];3(5):617–21. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22111743
Boggia J, Asayama K, Li Y, Hansen TW, Mena L, Schutte R. Cardiovascular risk stratification and blood pressure variability on ambulatory and home blood pressure measurement. Curr Hypertens Rep [Internet]. 2014 Sep [cited 2015 Sep 16];16(9):470. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25097109
Rowland T, Unnithan V. Stroke volume dynamics during progressive exercise in healthy adolescents. Pediatr Exerc Sci [Internet]. 2013 May [cited 2015 Sep 22];25(2):173–85. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23504977
Hansen TW, Thijs L, Li Y, Boggia J, Kikuya M, Björklund-Bodegård K, et al. Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations. Hypertension [Internet]. 2010 Apr [cited 2015 Sep 16];55(4):1049–57. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20212270
Krzesiński P, Stańczyk A, Gielerak G, Piotrowicz K. The hemodynamic patterns in hypertensive men and women of different age. J Hum Hypertens [Internet]. 2015 Jul 2 [cited 2015 Jul 22]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/26134620
Bristow M. Antiadrenergic Therapy of Chronic Heart Failure: Surprises and New Opportunities. Circulation [Internet]. 2003 Mar 4 [cited 2015 Sep 16];107(8):1100–2. Available from: http://circ.ahajournals.org/content/107/8/1100.full
