AmbTrack: KLINIČKI RELEVANTAN MOST IZMEĐU RURALNIH IZVORIŠTA POLENA I URBANIH IZAZOVA ALERGIJE
DOI:
https://doi.org/10.46793/PP260202005BKljučne reči:
ambrozija, aeroalergeni, urbano zagađenje, digitalno zdravlje, građanska nauka, rano upozoravanjeApstrakt
Ambrozija (Ambrosia artemisiifolia) je visoko potentan aeroalergen čija se sezona u Evropi uobičajeno preklapa sa periodom najčešće pojave alergijskog rinitisa i akutnih pogoršanja astme. U kliničkoj praksi se često primećuje paradoks gde pacijenti u urbanim sredinama prijavljuju teže simptome u poređenju sa stanovništvom u ruralnoj sredini, iako su primarna izvorišta ambrozije najčešće van gradova. Ovaj pregledni rad fokusira se na kliničke implikacije ruralno-urbanog gradijenta izloženosti i predstavlja AmbTrack projekat (Real-Time Monitoring and Molecular Characterization of Ambrosia Pollen Exposure through Citizen Tracking) kao konceptualni i operativni okvir koji objedinjuje aerobiološki monitoring, meteorološke uslove, podatke o zagađenju vazduha, daljinsku detekciju kao i prijavu simptoma putem mobilnih alata, zajedno sa informacijama o lokacijama ambrozije i trenutnom zdravstvenom stanju pacijenta/pojedinca sa alergijom na ambroziju. Ključna poruka za kliničku praksu je da se polen u gradu ne ponaša kao biološka čestica, jer interakcije sa zagađenjem (PM, NO2, O3), urbanim toplotnim ostrvima i mikroaerodinamikom gradskih ulica mogu pogoršati ekspresiju bolesti i produžiti vreme izloženosti. AmbTrack konceptualno predstavlja pristup koji omogućava pravovremena upozorenja i prelazak sa reaktivne na preventivnu terapiju, uz potencijalno unapređenje praćenja i lečenja pacijenata, racionalniju upotrebu lekova i smanjenje socio-ekonomskih posledica.
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