WHAT IS ABOUT COVID PNEUMONIA IN CHILDREN?

Authors

  • Zorica Živković Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia, Faculty of Pharmacy Novi Sad, Business Academy in Novi Sad, Novi Sad, Serbia
  • Olivera Ostojić Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Vesna Veković Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Ivana Ćurić Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Olivera Stojanović Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Ana Nešković Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Vera Aleksić Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia
  • Miodrag Lalošević Medical Center „Dr Dragiša Mišović“, Radiological Service, Belgrade, Serbia
  • Tijana Kosanović Medical Center „Dr Dragiša Mišović“, Radiological Service, Belgrade, Serbia
  • Zorica Marković Medical Center „Dr Dragiša Mišović“, Clinical Laboratory Service, Belgrade, Serbia
  • Iva Blagojević Perović Medical Center „Dr Dragiša Mišović“, Clinical Laboratory Service, Belgrade, Serbia

Keywords:

Covid19, pneumonia, children

Abstract

The authors present clinical symptoms, laboratory findings, radiographic pictures and the most important clinical data and outcomes of patients admitted to Medical Center „Dr Dragiša Mišović“, Children's Hospital for Lung Diseases and Tb, Belgrade, Serbia during the SARS COV2 pandemic from March 2020 to March 2021. Overall number of children hospitalized due to Covid19 infection was 734 from 16th of March 2020. until 8th of April 2021. Not all of them present with symptoms and signs of viral pneumonia due to corona viurs. We will describe clinical features and caracteristics of Covid pneumonia in 67 children hospitalized during autumn – winter season 2020/2021. The age range was from 2 to 18 years. The complete number of respresentative cases were confirmed by biochemical and heamatological markers, and positive PCR test respectivelly. During autumn winter season 2020/2021 Chest X ray and/or computerasied tomography (CT Scan) were performed in almost all children and remarkable results were obtained. Our experience was in accordance with worldwide data about risk factors for moderate to severe Covid pneumonia in children. Obesity, morbid obesity and comorbidities were verified as the most prominent risk factors. Speaking about the Covid pneumonia not mentioning multisystem inflammatory syndrome in children (MISC) it is imprtant to emphasize that all our patients recovered successfully with very mild protracted symptoms ocasionally.

References

World Health Organization, Naming the Coronavirus Disease (COVID-19) and the Virus That Causes It. (2020). Available online at: https://www. who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/ naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it (accessed October 11, 2020)

World Health Organization. Director-General's remarks at the media briefing on2019-nCoV on 11 February 2020. http://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020 (Accessed on February 12, 2020).

Wu Q, Xing Y, Shi L, et al. Coinfection and Other Clinical Characteristics of COVID-19 in Children. Pediatrics 2020; 146.

P, Johnson CL, Halabi KC, et al. Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York. JAMA Pediatr 2020; 174:e202430

.Hobbs CV, Martin LM, Kim SS, et al. Factors Associated with Positive SARS-CoV-2 Test Results in Outpatient Health Facilities and Emergency Departments Among Children and Adolescents Aged <18 Years - Mississippi, September-November 2020. MMWR Morb Mortal Wkly Rep 2020; 69:1925.

.Laxminarayan R, Wahl B, Dudala SR, et al. Epidemiology and transmission dynamics of COVID-19 in two Indian states. Science 2020; 370:691.

Goldstein E, Lipsitch M, Cevik M. On the Effect of Age on the Transmission of SARS-CoV-2 in Households, Schools, and the Community. J Infect Dis 2021; 223:362.

Otto WR, Geoghegan S, Posch LC, Bell LM, Coffin SE, Sammons JS, Harris RM, Odom John AR, Luan X, Gerber JS. The Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 in a Pediatric Healthcare Network in the United States. J Pediatric Infect Dis Soc. 2020;9(5):523.

Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020..Stokes EK, Zambrano LD, Anderson KN, Marder EP, Raz KM, El Burai Felix S, Tie Y, Fullerton KE .MMWR Morb Mortal Wkly Rep. 2020;69(24):759. Epub 2020 Jun 19

Liguoro I, Pilotto C, Bonanni M, Ferrari ME, Pusiol A, Nocerino A, Vidal E, Cogo P SARS-COV-2 infection in children and newborns: a systematic review. Eur J Pediatr. 2020;179 (7):1029. Epub May 2020 18

Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ, HLH Across Speciality Collaboration. COVID-19: consider cytokine storm syndromes and immunosuppression. UK Lancet. 2020;395 (10229):1033. Epub 2020 Mar 16.

Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ,D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A . Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses. J Pediatr. 2020;227:45. Epub 2020 Aug 20.

Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, Tong S. Epidemiology of COVID-19 Among Children in China.Pediatrics. 2020;145(6) Epub 2020 Mar 1

Venturini E, Palmas G, Montagnani C, Chiappini E, Citera F, Astorino V, Trapani S, Galli L Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection. J Pediatr. 2020;222:259. Epub 2020 May 19.

Zachariah P, Johnson CL, Halabi KC, Ahn D, Sen AI, Fischer A, Banker SL, Giordano M, Manice CS, Diamond R, Sewell TB, Schweickert AJ, Babineau JR, Carter RC, Fenster DB, Orange JS, McCann TA, Kernie SG, Saiman L, Columbia Pediatric COVID-19 Management Group . Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York. JAMA Pediatr. 2020;174(10):e202430. Epub 2020 Oct 5.

Sanna G, Serrau G, Bassareo PP, Neroni P, Fanos V, Marcialis MA Children's heart and COVID-19: Up-to-date evidence in the form of a systematic review. Eur J Pediatr. 2020;179 (7):1079. Epub 2020 May 30.

Giacomet V, Barcellini L, Stracuzzi M, Longoni E, Folgori L, Leone A, Zuccotti GV, COVID-19 Pediatric network . Gastrointestinal Symptoms in Severe COVID-19 Children. Pediatr Infect Dis J. 2020;39(10):e317.

Foust AM, McAdam AJ, Chu WC, Garcia-Pena P, Phillips GS, Plut D. Practical guide for pediatric pulmonologists on imaging management of pediatric patients with COVID-19. Pediatr. Pulmonol. (2020) 55:2213–24. doi: 10.1002/ppul.24870

Front. Pediatr., 14 December 2020 | https://doi.org/ 10.3389/fped.2020.616622

Shelmerdine SC, Lovrenski J, Caro-Domínguez P, Toso S, Collaborators of the European Society of Paediatric Radiology Cardiothoracic Imaging Taskforce Coronavirus disease 2019 (COVID-19) in children: a systematic review of imaging findings.Pediatr Radiol. 2020;50(9):1217. Epub 2020 Jun 18.

Nino G, Zember J, Sanchez-Jacob R, Gutierrez MJ, Sharma K, Linguraru MG Pediatric lung imaging features of COVID-19: A systematic review and meta-analysis.Pediatr Pulmonol. 2021;56(1):252. Epub 2020 Nov 2.

Chen Z, Fu J, Shu Q et al . Diagnosis and treatment recommendation for pediatric coronavirus disease-19. Zhejiang Da Xue Xue Bao Yi Xue Ban 2020; 49:1–8

Chen F, Liu ZS, Zhang FR et al . First case of severe childhood novel coronavirus pneumonia in China. Zhonghua Er Ke Za Zhi 2020; 58:E005

Downloads

Published

03/10/2022

Issue

Prev Ped 2021: 7(1-2)

Section

Original Articles